CAS Number: 9011-18-1
pK Chemicals produces Dextran Sulphate. Dextran Sulphate is a polyanionic derivative of Dextran. It is supplied as a white, sodium salt powder, stabilized by a small amount of phosphate. Dextran Sulphate is freely soluble in water and salt solutions forming a stable, clear solution, which may be sterilized by sterile filtration. The powder is stable for more than 6 years if stored at room temperature in airtight containers.
PKC manufactures Dextran Sulphates of several molecular weights ranging from mean Mw 5k to mean Mw >1000k.
The high purity and reproducible quality of Dextran Sulphate makes it suitable for many applications in molecular biology and the health-care sector. The following properties and applications are well documented:
• Accelerates hybridization rates
• Anti-coagulant properties
• Anti-viral properties
• Interaction with lipoproteins, enzymes and cells
• Cosmetic applications
• Stabilizer of proteins
Test/Characteristic | Limit | Test Method |
Appearance | Comparable to ref. | EP |
Solubility | Clear and particle free | EP |
Turbidity, NTU | ≤ 5.0 | EP |
Identification | Complies | EP |
Sulphur content, % S | 16.0-19.0 | Internal |
Specific optical rotation; ° | +90 to +105 | EP |
Specific viscosity | ≥ 0.32 | EP |
Absorbance | ≤ 0.15 | EP and USP |
Loss on drying, % | ≤ 7 | EP and USP |
pH, (1 % w/v sol) | 6.0-8.0 | EP |
Free Sulphate; % | ≤ 0.5 | Internal |