Dextran Sulphate Sodium Salt

CAS Number: 9011-18-1

pK Chemicals produces Dextran Sulphate. Dextran Sulphate is a polyanionic derivative of Dextran. It is supplied as a white, sodium salt powder, stabilized by a small amount of phosphate. Dextran Sulphate is freely soluble in water and salt solutions forming a stable, clear solution, which may be sterilized by sterile filtration. The powder is stable for more than 6 years if stored at room temperature in airtight containers.

PKC manufactures Dextran Sulphates of several molecular weights ranging from mean Mw 5k to mean Mw >1000k.

The high purity and reproducible quality of Dextran Sulphate makes it suitable for many applications in molecular biology and the health-care sector. The following properties and applications are well documented:

• Accelerates hybridization rates
• Anti-coagulant properties
• Anti-viral properties
• Interaction with lipoproteins, enzymes and cells
• Cosmetic applications
• Stabilizer of proteins



Test/Characteristic Limit Test Method
Appearance Comparable to ref. EP
Solubility Clear and particle free EP
Turbidity, NTU ≤ 5.0 EP
Identification Complies EP
Sulphur content, % S 16.0-19.0 Internal
Specific optical rotation; ° +90 to +105 EP
Specific viscosity ≥ 0.32 EP
Absorbance ≤ 0.15 EP and USP
Loss on drying, % ≤ 7 EP and USP
pH, (1 % w/v sol) 6.0-8.0 EP
Free Sulphate; % ≤ 0.5 Internal

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