Physical characteristics of CM-Dextran :
CM-Dextran is a polyanionic derivative of Dextran. It is supplied as the sodium salt. CM-Dextran is a white powder and is freely soluble in water and salt solutions. As the carboxymethyl groups of CM-Dextran are attached by a stable O-ether linkage, no stabilizer is needed and a solution may be sterilized by autoclaving. The high purity and reproducible quality commend CM-Dextran for many applications in the pharmaceutical, biotechnology and cosmetic industry.
Chemical characeristics of CM-Dextran:
Dextran sodium sulphate is prepared by reaction of dextran with chloro-acetic acid, followed by careful purification.
The molecular weight denotation of Dextran sodium sulphate is the molecular weight in KDa divided by 1000. I.e. Dextran sodium sulphate 40 is Dextran sodium sulphate 40.000 KDa.
Typical denotations are: 1,3,5,10,40,60,70,110,150, 250 and 500.
- Carrier for biosensor surfaces
- Preparation of low-toxic API formulations
- Stable non-immunogenic additive
- Stabilizer of proteins and sensitive biopolymers
- Carriage and slow-release of kations